Prof Guzik added: “This could help with precision medicine, so that we can target more intensive therapies to prevent the development of cognitive impairment in patients most at risk,” he said. “Moreover, by looking at these specific regions of the brain, we may be able to predict who will develop memory loss and dementia faster in the context of high blood pressure.”
“Studying the genes and proteins in these brain structures could help us understand how high blood pressure affects the brain and causes cognitive problems. “We hope that our findings may help us to develop new ways to treat cognitive impairment in people with high blood pressure. “When we checked our findings by studying a group of patients in Italy who had high blood pressure, we found that the parts of the brain we had identified were indeed affected. “We thought these areas might be where high blood pressure affects cognitive function such as memory loss, thinking skills and dementia. Lead author Tomasz Guzik, professor of cardiovascular medicine at the University of Edinburgh and Jagiellonian University Medical College in Krakow, Poland, said: “By using this combination of imaging, genetic and observational approaches we have identified specific parts of the brain that are affected by increases in blood pressure, including areas called the putamen and specific white matter regions. Their findings were then checked against another group of patients in Italy. Researchers studied analysis of brain scans, genetics and data from thousands of patients. In the future, academics hope that the findings will help predict memory loss and dementia.
Experts will now look at the specific parts of the brain in more detail with a view to finding new ways to treat mental decline among people with high blood pressure. It is the first time these regions have been identified by scientists. Scientists have identified the regions of the brain that are damaged by high blood pressure and may contribute to the development of dementia.Įxperts said the finding is a “step forward in our understanding of the concerning link between high blood pressure and cognitive decline”.
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